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KMID : 1134120110140020160
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Journal of Breast Cancer
2011 Volume.14 No. 2 p.160 ~ p.164
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Primary Acinic Cell Carcinoma of the Breast: A Case Report with an Immunohistochemical and Ultrastructural Studies
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Chang Eun-Deok
Lee Eun-Jung
Lee Ah-Won
Kim Jeong-Soo
Kang Chang-Suk
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Abstract
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Acinic cell carcinoma (ACC) of the breast is extremely rare and is characterized by widespread acinar cell-like differentiation. We report of a 39-year-old woman presented with a palpable breast mass with significant morphological, immunohistochemical and ultrastructural findings. Histologically, ACC showed a diffuse glandular infiltrative pattern, with small acinar or glandular structures mixed with solid nests. Neoplastic cells were monotonous proliferation of cells with a granular or clear cytoplasm, resembling acinar cells of the salivary glands or Paneth cells. Both glandular and solid tumor cell populations were strongly positive for lysozyme and α-1-antitrypsin.
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KEYWORD
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Acinic cell carcinoma, Breast neoplasms, Electron microscopy, Immunohistochemistry
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